Clinical Trial Management | Newcastle Medical Nutrition Unit

The University of Newcastle is positioned at the forefront of nutraceuticals, dietary supplements and functional foods research. Leveraging a multi-disciplinary research team in Respiratory Medicine, Cardiology, Nutrition and Dietetics, Human Physiology, Medical Biochemistry, Human Nutrition and Food Science, the University provides internationally recognised expertise to design and conduct health claims testing via clinical trial management.

Clinical Trials ManagementCompanies considering clinical trials which require state of the art facilities, dedicated contract research and key opinion leader involvement need look no further. Through Newcastle Innovation, locally-based experts are able to provide comprehensive, turnkey research and development solutions that support nutraceutical claims.

Experts have partnered with companies well known both domestically and internationally, including:

  • Arnott’s
  • Campbell Foods
  • Macadamia Society of Australia
  • Meat & Livestocks of Australia
  • Meadow Lea Foods
  • Pathways Internationals

Hunter Region Advantage

The Hunter region is located close to Sydney, and is home to a stable and well characterised population featuring a mixture of ages, socio-economic statuses and urban/rural locations, making the Hunter an ideal microcosm for population based studies in Australia.

The Newcastle Medical Nutrition Unit is founded upon a strong technical, educational and infrastructured base, across a well established multi-campus research hub. It brings together researchers and medical professionals from the University of Newcastle, Hunter New England Health and the Calvary Mater Newcastle Hospital in order to work across the full spectrum of research, nurturing translational outcomes with commercial value and benefit to the community.

The Services

Professor Manohar Garg, who is internationally recognised with extensive experience in the design and management of health claims trials, leads clinical trials management services. The objective of his group is to bring researchers working in the area of nutrition, dietary supplements and functional foods together under one umbrella, for companies who need nutritional trials and expert academic advice.

Clinical Trials ResearchThe comprehensive services include:

1. Protocol and Clinical Trial Design
2. Ethics Committee Management
3. Literature Review and Reporting
4. Recruitment and Site Management
5. Blood Testing and Tissue Sampling
6. Anthropometry and Body Composition
7. Bone density testing
8. Data Management and Statistical Analysis
9. Reporting and Dissemination
10. Publishing

Contract Research

Product health claims are essential for commercial success. Clinical trials and metabolic studies on nutraceuticals, dietary supplements and functional foods have become essential in supporting marketing strategies. All of these requirements can be facilitated by Newcastle Innovation through our facility network, our resource base and our world class research team.

The Opportunity

Established trials for functional foods and nutritional supplements are available to companies as contract research. The University has access to a wide demo-graphic base including diabetics, obese patients with hyperlipidemia, and inflammatory health problems.

Companies needing nutritional trials, expert academic advice and specifically trained personnel to design, conduct and analyse experiments have the University of Newcastle at their disposal for clinical trial management.

 Clinical Trials ManagementEstablished trials for nutrition include:

  • Functional foods
  • Dietary supplements
  • Dietetic interventions
  • Physical activity & exercise

Current research projects include:

  • Phytosterols and cardiovascular health
  • Fish oil in human health & disease
  • Role of dietary supplements in weight loss and  maintenance
  • Resveratrol and virus-induced asthma
  • Brain dysfunction and neuroprotective potential of  resveratrol and DHA
  • Weight loss and asthma
  • Weight loss trials across varying lifestyles and stages.

Core Research Capabilities:

  • Cardiovascular Disease
  • Weight Loss and Obesity
  • Diabetes
  • Asthma
  • Alzheimer’s
  • Anti-inflammatory Diseases
  • Dietary assessment intake
  • Biostatistics

Tools and equipment:

  • DEXA
  • Pulse Wave Velocity for vascular studies
  • Gas Chromatography
  • Whole Blood Aggregometer
  • Bioelectric Impedance
  • High Performance Liquid Chromatography
  • Qualitative and quantitative PCR
  • Cell/Tissue Culture
  • Freeze dryer
  • Cell lines and animal models
  • Zetasizer

Collaborators and Facilities:

  • University of Newcastle
  • Hunter Medical Research Institute
  • John Hunter Hospital
  • Calvary Mater Newcastle
  • Newcastle Innovation